2024
Original articles
- Transcript splicing optimizes the thymic self-antigen repertoire to suppress autoimmunity
- Ryunosuke Muro, Takeshi Nitta, Sachiko Nitta, Masayuki Tsukasaki, Tatsuo Asano, Kenta Nakano, Tadashi Okamura, Tomoki Nakashima, Kazuo Okamoto, and Hiroshi Takayanagi
- J Clin Invest. 134(20):e179612. 2024.
- Ryunosuke Muro, Takeshi Nitta, Sachiko Nitta, Masayuki Tsukasaki, Tatsuo Asano, Kenta Nakano, Tadashi Okamura, Tomoki Nakashima, Kazuo Okamoto, and Hiroshi Takayanagi
- Disulfiram ameliorates bone loss in ovariectomized mice by suppressing osteoclastogenesis.
- Tatsuyuki Fukui, Asuka Terashima, Yasunori Omata, Ryota Chijimatsu, Kazuo Okamoto, Masayuki Tsukasaki, Yukiko Fukuda, Tadayoshi Hayata, Akiyoshi Saitoh, Etsuko Toda, Hiroshi Takayanagi, Sakae Tanaka, Yuya Terashima, Taku Saito
- J Bone Miner Metab 2024. doi: 10.1007/s00774-024-01555-x.
- Tatsuyuki Fukui, Asuka Terashima, Yasunori Omata, Ryota Chijimatsu, Kazuo Okamoto, Masayuki Tsukasaki, Yukiko Fukuda, Tadayoshi Hayata, Akiyoshi Saitoh, Etsuko Toda, Hiroshi Takayanagi, Sakae Tanaka, Yuya Terashima, Taku Saito
- The periosteum provides a stromal defence against cancer invasion into the bone
- Kazutaka Nakamura, Masayuki Tsukasaki*(corresponding author), Takaaki Tsunematsu, Minglu Yan, Yutaro Ando, Nam Cong-Nhat Huynh, Kyoko Hashimoto, Qiao Gou, Ryunosuke Muro, Ayumi Itabashi, Takahiro Iguchi, Kazuo Okamoto, Takashi Nakamura, Kenta Nakano, Tadashi Okamura, Tomoya Ueno, Kosei Ito, Naozumi Ishimaru, Kazuto Hoshi, Hiroshi Takayanagi
- Nature 2024. doi: 10.1038/s41586-024-07822-1.
- Kazutaka Nakamura, Masayuki Tsukasaki*(corresponding author), Takaaki Tsunematsu, Minglu Yan, Yutaro Ando, Nam Cong-Nhat Huynh, Kyoko Hashimoto, Qiao Gou, Ryunosuke Muro, Ayumi Itabashi, Takahiro Iguchi, Kazuo Okamoto, Takashi Nakamura, Kenta Nakano, Tadashi Okamura, Tomoya Ueno, Kosei Ito, Naozumi Ishimaru, Kazuto Hoshi, Hiroshi Takayanagi
- Caspase-11 mediated inflammasome activation in macrophages by systemic infection of A. actinomycetemcomitans exacerbates arthritis
- Tokuju Okano, Hiroshi Ashida, Noriko Komatsu, Masayuki Tsukasaki, Tamako Iida, Marie Iwasawa, Yuto Takahashi, Yasuo Takeuchi, Takanori Iwata, Miwa Sasai, Masahiro Yamamoto, Hiroshi Takayanagi, Toshihiko Suzuki
- International Journal of Oral Science 16(1):54, 2024.
- Tokuju Okano, Hiroshi Ashida, Noriko Komatsu, Masayuki Tsukasaki, Tamako Iida, Marie Iwasawa, Yuto Takahashi, Yasuo Takeuchi, Takanori Iwata, Miwa Sasai, Masahiro Yamamoto, Hiroshi Takayanagi, Toshihiko Suzuki
- Oncostatin M-driven macrophage-fibroblast circuits as a drug target in autoimmune arthritis
- Nam Cong-Nhat Huynh, Rui Ling, Masatsugu Komagamine, Tianshu Shi, Masayuki Tsukasaki, Kotaro Matsuda, Kazuo Okamoto, Tatsuo Asano, Ryunosuke Muro, Warunee Pluemsakunthai, George Kollias, Yuko Kaneko, Tsutomu Takeuchi, Sakae Tanaka, Noriko Komatsu, Hiroshi Takayanagi
- Inflammation and Regeneration 44(1):36. 2024.
- Nam Cong-Nhat Huynh, Rui Ling, Masatsugu Komagamine, Tianshu Shi, Masayuki Tsukasaki, Kotaro Matsuda, Kazuo Okamoto, Tatsuo Asano, Ryunosuke Muro, Warunee Pluemsakunthai, George Kollias, Yuko Kaneko, Tsutomu Takeuchi, Sakae Tanaka, Noriko Komatsu, Hiroshi Takayanagi
- Synchronized development of thymic eosinophils and thymocytes
- Ayami Ota, Takahiro Iguchi, Sachiko Nitta, Ryunosuke Muro, Nanami Mino, Masayuki Tsukasaki, Josef M Penninger, Takeshi Nitta, Hiroshi Takayanagi
- International Immunology 2024. doi: 10.1093/intimm/dxae037.
- Ayami Ota, Takahiro Iguchi, Sachiko Nitta, Ryunosuke Muro, Nanami Mino, Masayuki Tsukasaki, Josef M Penninger, Takeshi Nitta, Hiroshi Takayanagi
- The neutrophil–osteogenic cell axis promotes bone destruction in periodontitis
- Yutaro Ando, Masayuki Tsukasaki*(corresponding author), Nam Cong-Nhat Huynh, Shizao Zang, Minglu Yan, Ryunosuke Muro, Kazutaka Nakamura, Masatsugu Komagamine, Noriko Komatsu, Kazuo Okamoto, Kenta Nakano, Tadashi Okamura, Akira Yamaguchi, Kazuyuki Ishihara, Hiroshi Takayanagi
- International Journal of Oral Science 16(18) 1-9, 2024.
- Yutaro Ando, Masayuki Tsukasaki*(corresponding author), Nam Cong-Nhat Huynh, Shizao Zang, Minglu Yan, Ryunosuke Muro, Kazutaka Nakamura, Masatsugu Komagamine, Noriko Komatsu, Kazuo Okamoto, Kenta Nakano, Tadashi Okamura, Akira Yamaguchi, Kazuyuki Ishihara, Hiroshi Takayanagi
2023
Original articles
- Identification of an intronic enhancer regulating RANKL expression in osteocytic cells
- Minglu Yan, Masayuki Tsukasaki*(corresponding author), Ryunosuke Muro, Yutaro Ando, Kazutaka Nakamura, Noriko Komatsu, Takeshi Nitta, Tadashi Okamura, Kazuo Okamoto, Hiroshi Takayanagi
- Bone Research 11(1):43. 2023.
- Minglu Yan, Masayuki Tsukasaki*(corresponding author), Ryunosuke Muro, Yutaro Ando, Kazutaka Nakamura, Noriko Komatsu, Takeshi Nitta, Tadashi Okamura, Kazuo Okamoto, Hiroshi Takayanagi
2022
Original articles
- ETS1 governs pathological tissue-remodeling programs in disease-associated fibroblasts
- Minglu Yan,Noriko Komatsu, Ryunosuke Muro, Nam Cong-Nhat Huynh, Yoshihiko Tomofuji, Yukinori Okada, Hiroshi I. Suzuki, Hiroyuki Takaba, Riko Kitazawa, Sohei Kitazawa, Warunee Pluemsakunthai, Yuichi Mitsui, Takashi Satoh, Tadashi Okamura, Takeshi Nitta, Sin-Hyeog Im, Chan Johng Kim, George Kollias, Sakae Tanaka, Kazuo Okamoto, Masayuki Tsukasaki, Hiroshi Takayanagi
- Nature Immunology 23(9):1330-1341, 2022.
- Minglu Yan,Noriko Komatsu, Ryunosuke Muro, Nam Cong-Nhat Huynh, Yoshihiko Tomofuji, Yukinori Okada, Hiroshi I. Suzuki, Hiroyuki Takaba, Riko Kitazawa, Sohei Kitazawa, Warunee Pluemsakunthai, Yuichi Mitsui, Takashi Satoh, Tadashi Okamura, Takeshi Nitta, Sin-Hyeog Im, Chan Johng Kim, George Kollias, Sakae Tanaka, Kazuo Okamoto, Masayuki Tsukasaki, Hiroshi Takayanagi
- Periosteal stem cells control growth plate stem cells during postnatal skeletal growth
- Masayuki Tsukasaki, Noriko Komatsu, Takako Negishi-Koga, Nam Cong-Nhat Huynh, Ryunosuke Muro, Yutaro Ando, Yuka Seki, Asuka Terashima, Warunee Pluemsakunthai, Takeshi Nitta, Takashi Nakamura, Tomoki Nakashima, Shinsuke Ohba, Haruhiko Akiyama, Kazuo Okamoto, Roland Baron, Hiroshi Takayanagi
- Nature Communications 13(1) :4166, 2022.
- Masayuki Tsukasaki, Noriko Komatsu, Takako Negishi-Koga, Nam Cong-Nhat Huynh, Ryunosuke Muro, Yutaro Ando, Yuka Seki, Asuka Terashima, Warunee Pluemsakunthai, Takeshi Nitta, Takashi Nakamura, Tomoki Nakashima, Shinsuke Ohba, Haruhiko Akiyama, Kazuo Okamoto, Roland Baron, Hiroshi Takayanagi
- Skeletal muscle mitoribosomal defects are linked to low bone mass caused by bone marrow inflammation in male mice
- Jingwen Tian, Hyo Kyun Chung, Ji Sun Moon, Ha Thi Nga, Ho Yeop Lee, Jung Tae Kim, Joon Young Chang, Seul Gi Kang, Dongryeol Ryu, Xiangguo Che, Je‐Yong Choi, Masayuki Tsukasaki, Takayoshi Sasako, Sang‐Hee Lee, Minho Shong, Hyon‐Seung Yi
- Journal of Cachexia, Sarcopenia and Muscle 13(3):1785-1799. 2022.
- Jingwen Tian, Hyo Kyun Chung, Ji Sun Moon, Ha Thi Nga, Ho Yeop Lee, Jung Tae Kim, Joon Young Chang, Seul Gi Kang, Dongryeol Ryu, Xiangguo Che, Je‐Yong Choi, Masayuki Tsukasaki, Takayoshi Sasako, Sang‐Hee Lee, Minho Shong, Hyon‐Seung Yi
Review articles
- Osteoclast biology in the single-cell era
- Masayuki Tsukasaki, Hiroshi Takayanagi
- Inflammation and Regeneration 42(1):27, 2022.
- Masayuki Tsukasaki, Hiroshi Takayanagi
2021
Original articles
- Cytokine profile in patients with chronic non-bacterial osteomyelitis, juvenile idiopathic arthritis, and insulin-dependent diabetes mellitus
- Mikhail M. Kostik, Maria A. Makhova, Alexei S. Maletin, Shamai M. Magomedova, Lybov S. Sorokina, Masayuki Tsukasaki, Kazuo Okamoto, Hiroshi Takayanagi, Dmitriy S. Vasiliev, Darya I. Kozlova, Alexander Yu. Mushkin
- Cytokine 143:155521-155521, 2021.
- Mikhail M. Kostik, Maria A. Makhova, Alexei S. Maletin, Shamai M. Magomedova, Lybov S. Sorokina, Masayuki Tsukasaki, Kazuo Okamoto, Hiroshi Takayanagi, Dmitriy S. Vasiliev, Darya I. Kozlova, Alexander Yu. Mushkin
- Plasma cells promote osteoclastogenesis and periarticular bone loss in autoimmune arthritis
- Noriko Komatsu, Stephanie Win, Minglu Yan, Nam Cong-Nhat Huynh, Shinichiro Sawa, Masayuki Tsukasaki, Asuka Terashima, Warunee Pluemsakunthai, George Kollias, Tomoki Nakashima, Hiroshi Takayanagi
- Journal of Clinical Investigation 131(6):e143060. 2021.
- Noriko Komatsu, Stephanie Win, Minglu Yan, Nam Cong-Nhat Huynh, Shinichiro Sawa, Masayuki Tsukasaki, Asuka Terashima, Warunee Pluemsakunthai, George Kollias, Tomoki Nakashima, Hiroshi Takayanagi
2020
Original articles
- Stepwise cell fate decision pathways during osteoclastogenesis at single-cell resolution
- Masayuki Tsukasaki, Nam Cong-Nhat Huynh, Kazuo Okamoto, Ryunosuke Muro, Asuka Terashima, Yoshitaka Kurikawa, Noriko Komatsu, Warunee Pluemsakunthai, Takeshi Nitta, Takaya Abe, Hiroshi Kiyonari, Tadashi Okamura, Mashito Sakai, Toshiya Matsukawa, Michihiro Matsumoto, Yasuhiro Kobayashi, Josef M. Penninger, Hiroshi Takayanagi
- Nature Metabolism 2(12):1382-1390, 2020.
- Masayuki Tsukasaki, Nam Cong-Nhat Huynh, Kazuo Okamoto, Ryunosuke Muro, Asuka Terashima, Yoshitaka Kurikawa, Noriko Komatsu, Warunee Pluemsakunthai, Takeshi Nitta, Takaya Abe, Hiroshi Kiyonari, Tadashi Okamura, Mashito Sakai, Toshiya Matsukawa, Michihiro Matsumoto, Yasuhiro Kobayashi, Josef M. Penninger, Hiroshi Takayanagi
- OPG Production Matters Where It Happened
- Masayuki Tsukasaki, Tatsuo Asano, Ryunosuke Muro, Nam Cong-Nhat Huynh, Noriko Komatsu, Kazuo Okamoto, Kenta Nakano, Tadashi Okamura, Takeshi Nitta, Hiroshi Takayanagi
- Cell Reports 32(10):108124, 2020.
- Masayuki Tsukasaki, Tatsuo Asano, Ryunosuke Muro, Nam Cong-Nhat Huynh, Noriko Komatsu, Kazuo Okamoto, Kenta Nakano, Tadashi Okamura, Takeshi Nitta, Hiroshi Takayanagi
Review articles
- RANKL and osteoimmunology in periodontitis
- Masayuki Tsukasaki
- Journal of Bone and Mineral Metabolism 39(1):82-90. 2020.
- Masayuki Tsukasaki
2019
Review articles
- Osteoimmunology: evolving concepts in bone-immune interactions in health and disease.
- Masayuki Tsukasaki, Hiroshi Takayanagi
- Nature Reviews Immunology 19(10):626-642, 2019.
- Masayuki Tsukasaki, Hiroshi Takayanagi
2018
Original articles
- Host defense against oral microbiota by bone-damaging T cells
- Masayuki Tsukasaki, Noriko Komatsu, Kazuki Nagashima, Takeshi Nitta, Warunee Pluemsakunthai, Chisa Shukunami, Yoichiro Iwakura, Tomoki Nakashima, Kazuo Okamoto, Hiroshi Takayanagi
- NatureCommunications 9(1):701, 2018.
- Masayuki Tsukasaki, Noriko Komatsu, Kazuki Nagashima, Takeshi Nitta, Warunee Pluemsakunthai, Chisa Shukunami, Yoichiro Iwakura, Tomoki Nakashima, Kazuo Okamoto, Hiroshi Takayanagi
2017
Original articles
- LOX Fails to Substitute for RANKL in Osteoclastogenesis
- Masayuki Tsukasaki, Koki Hamada, Kazuo Okamoto, Kazuki Nagashima, Asuka Terashima, Noriko Komatsu, Stephanie J. Win, Tadashi Okamura, Takeshi Nitta, Hisataka Yasuda, Josef M. Penninger, Hiroshi Takayanagi
- Journal of Bone and Mineral Research 32(3):434-439, 2017.
- Masayuki Tsukasaki, Koki Hamada, Kazuo Okamoto, Kazuki Nagashima, Asuka Terashima, Noriko Komatsu, Stephanie J. Win, Tadashi Okamura, Takeshi Nitta, Hisataka Yasuda, Josef M. Penninger, Hiroshi Takayanagi
2016
Original articles
- Expression of nephronectin is enhanced by 1α,25-dihydroxyvitamin D3.
- Katsuhiro Hiranuma, Atsushi Yamada, Tamaki Kurosawa, Ryo Aizawa, Dai Suzuki, Yoshiro Saito, Ryo Nagahama, Mikiko Ikehata, Masayuki Tsukasaki, Naoko Morimura, Daichi Chikazu, Koutaro Maki, Tatsuo Shirota, Masamichi Takami, Matsuo Yamamoto, Takehiko Iijima, Ryutaro Kamijo
- FEBS Open Bio 6(9):914-918, 2016.
- Katsuhiro Hiranuma, Atsushi Yamada, Tamaki Kurosawa, Ryo Aizawa, Dai Suzuki, Yoshiro Saito, Ryo Nagahama, Mikiko Ikehata, Masayuki Tsukasaki, Naoko Morimura, Daichi Chikazu, Koutaro Maki, Tatsuo Shirota, Masamichi Takami, Matsuo Yamamoto, Takehiko Iijima, Ryutaro Kamijo
2013
Original articles
- BMP-2 Induced Expression of Alx3 That Is a Positive Regulator of Osteoblast Differentiation
- Takashi Matsumoto, Atsushi Yamada, Ryo Aizawa, Dai Suzuki, Masayuki Tsukasaki, Wataru Suzuki, Mutsuko Nakayama, Koutaro Maki, Matsuo Yamamoto, Kazuyoshi Baba, Ryutaro Kamijo
- PLoS One 8(6) e68774, 2013.
- Takashi Matsumoto, Atsushi Yamada, Ryo Aizawa, Dai Suzuki, Masayuki Tsukasaki, Wataru Suzuki, Mutsuko Nakayama, Koutaro Maki, Matsuo Yamamoto, Kazuyoshi Baba, Ryutaro Kamijo
2012
Original articles
- Nephronectin expression is regulated by SMAD signaling in osteoblast-like MC3T3-E1 cells
- Masayuki Tsukasaki, Atsushi Yamada, Kentaro Yoshimura, Agasa Miyazono, Matsuo Yamamoto, Masamichi Takami, Yoichi Miyamoto, Naoko Morimura, Ryutaro Kamijo
- Biochemical and Biophysical Research Communications 425(2): 390-392, 2012.
- Masayuki Tsukasaki, Atsushi Yamada, Kentaro Yoshimura, Agasa Miyazono, Matsuo Yamamoto, Masamichi Takami, Yoichi Miyamoto, Naoko Morimura, Ryutaro Kamijo
- Cdc42 is required for chondrogenesis and interdigital programmed cell death during limb development
- Ryo Aizawa, Atsushi Yamada, Dai Suzuki, Tadahiro Iimura, Hidetoshi Kassai, Takeshi Harada, Masayuki Tsukasaki, Gou Yamamoto, Tetsuhiko Tachikawa, Kazuki Nakao, Matsuo Yamamoto, Akira Yamaguchi, Atsu Aiba, Ryutaro Kamijo
- Mechanisms of Development 129(1-4): 38-50, 2012.
- Ryo Aizawa, Atsushi Yamada, Dai Suzuki, Tadahiro Iimura, Hidetoshi Kassai, Takeshi Harada, Masayuki Tsukasaki, Gou Yamamoto, Tetsuhiko Tachikawa, Kazuki Nakao, Matsuo Yamamoto, Akira Yamaguchi, Atsu Aiba, Ryutaro Kamijo
2011
Original articles
- Expression of POEM, a positive regulator of osteoblast differentiation, is suppressed by TNF-α.
- Masayuki Tsukasaki, Atsushi Yamada, Dai Suzuki, Ryo Aizawa, Agasa Miyazono, Yoichi Miyamoto, Tetsuo Suzawa, Masamichi Takami, Kentaro Yoshimura, Naoko Morimura, Matsuo Yamamoto, Ryutaro Kamijo
- Biochemical and Biophysical Research Communications 410(4): 766-770, 2011.
- Masayuki Tsukasaki, Atsushi Yamada, Dai Suzuki, Ryo Aizawa, Agasa Miyazono, Yoichi Miyamoto, Tetsuo Suzawa, Masamichi Takami, Kentaro Yoshimura, Naoko Morimura, Matsuo Yamamoto, Ryutaro Kamijo